![]() ![]() Here he speaks of his passion for medicine and for his. ![]() deCODE is well positioned to lead the way in generating and analyzing whole sequence data for large scale studies’. Outspoken doctor Kri Stefnsson founded Iceland's deCODE Genetics to use its citizens' genealogy in the hunt for human disease genes. Background: Rare missense mutations in the gene encoding coatomer subunit alpha (COPA) have recently been shown to cause autoimmune interstitial lung, joint and kidney disease, also known as COPA syndrome, under a dominant mode of inheritance. Sequencing entire human genomes enables a detailed understanding of the rare as well as common variations that impact disease. Moreover, our ability to genotype, or read specific ‘letters’ in the genome, is constantly and rapidly increasing. ‘Our advantage arises from the complexity of the challenge’, they affirm: ‘The common diseases – such as heart attack, asthma, stroke and cancer – arise from the interplay of multiple genetic and environmental and lifestyle factors. Kari Stefansson, founder of deCODE Genetics, during a press briefing on. With the distinctive ability to correlate two large sets of data: on variations in the sequence of the genome on the one hand, and on variations in phenotype or condition, such as a disease or some physical trait, on the other. The milestone in genome sequencing comes from deCODE Genetics, a biopharmaceutical company in Reykjavík, Iceland. The genomes were sequenced at deCODE genetics in Reykjavik, Iceland, and the Wellcome. Gruff, unabashedly opinionated, controversial, and armed with an acerbic wit. ![]() That’s why deCODE genetics is nowadays a global leader in analysing and understanding the human genome. Halldorsson and Kari Stefansson are at deCODE genetics, Reykjavik, Iceland. Through its screening service and extensive genetic analysis of the virus, Reykjavik-based biopharmaceutical company deCODE has become a linchpin of Icelandic COVID-19 screening efforts. Kari Stefansson, founder of deCODE genetics in Reykjavik, Iceland, discusses his firms recent emergence from bankruptcy and its current concentration in. Putting together a genealogy database covering the entire present day population and stretching back to the founding of the country more than 1000 years ago, they’ve obtained and extraordinary map, that enables them to impute or predict genotypes using the genealogies, multiplying many-fold the amount of data that they can derive from genotyping and sequencing. Since the founding of the company in 1996, deCODE have gathered genotypic and medical data from more than 160,000 people, comprising well over half of the adult population of Iceland. Their name is deCODE and the company’s Founder, Kári Stefánsson, is recognized all over the world as a leading figure in human genetics: he will trip from Reykjavik to Milan, and give the opening remarks to the first Technology Forum Life Sciences, on Tuesday October 13th. Their Headquartered is in Reykjavik, Iceland: that’s perhaps the key reason of their success. The Iceland’s star of human genetics: Kári Stefánsson will open TF Life Sciences ![]()
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Pain and pleasure tattoo prices1/22/2024 ![]() Line, blend, fill and shade your next masterpiece with precision when you invest in durable and sterile tattoo needles from the best names in the business. Genital male piercings.Look no further than Painful Pleasures for the widest selection of professional tattoo needles online, from affordable mainstays to top-tier premium tattoo needles. Urogenital infection as a risk factor for male infertility. A cross-sectional study of men with genital piercings. Genital piercings in the context of acute sexual assault. Genital piercing and sexually transmitted infections. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Allow your pubic hair to get tangled in the jewelry.Play with or remove the jewelry until the piercing’s healed (about 3 months).Play sports or engage in other vigorous activity so that the penis isn’t jostled around or injured. ![]() Use antiseptic rinses or soaps on the piercing.Use alcohol-based rinses to clean the area.Have sex (oral, genital, or anal) or masturbate until the initial pain and swelling have gone down. ![]() Use condoms or other protection (after initial pain and swelling have gone down) until the area’s fully healed.Take clothes off and put them on carefully.Keep the penis from getting wet while you shower.Pat your penis dry with a clean paper towel any time you rinse it.Gently wash and rinse away any crust that forms.Rinse the piercing at least twice a day with distilled water and a saline solution.Wash your hands with gentle soap and warm water before touching the area.Cover the area with a bandage, and change it at least once a day.Proper cleaning is crucial to the success of your piercing. Reverse PA: the opposite of Prince Albert, with jewelry entering the urethra and exiting through the top of the shaft.Pubic: consists of a piece of jewelry through any part of the area around the base of the penis.Prince Albert: goes in through the opening where pee comes out, called the urethra, and comes out through the bottom of the penis shaft just behind the glans.Magic cross: consists of 2 to 3 piercings through the glans, usually with two barbells crossing each other with four beads poking out from under the skin.Lorum: done horizontally or vertically on the underside of the penis where the base of the shaft meets the scrotum.Hafada (scrotal): done anywhere on your scrotum, often in the middle front of your scrotum along the scrotal raphe.Guiche (perineum): runs horizontally through your perineum, the skin underneath your scrotum between your buttocks and anus.Frenum: done horizontally just behind the glans beneath the shaft, called the frenulum, or in several horizontal rows along the bottom of the shaft.Foreskin: done through the foreskin if you’re not circumcised, with jewelry placed where the foreskin covers the glans or down toward the shaft.Dydoe/king’s crown: done through the ridge at the base of the penis head, running vertically through the ridge.Deep shaft: typically an ampallang, apadravya, or reverse Prince Albert done down the shaft toward the penis base.Ampallang: pierced horizontally left to right or vice versa through the glans.Apadravya: pierced vertically through the glans, from top to bottom or vice versa.There are many different ways to pierce the penis, and each piercing has its own name: ![]() Penis piercing is often used as an umbrella term. ![]() James avery artisan jewelry live oak1/22/2024 ![]() ![]() Whether they wear birthstones, tiny gold earrings or big silver dangles, our customers create great looks with earrings! Need a little inspiration? Search #myjamesavery and you'll see just what we mean. 132, San Antonio, TX 78253 - hours, address, map, directions, phone number, customer ratings and reviews. Think cute studs and ear posts are only for little girls? Think again! Women of all ages love to wear petite ear posts and mix and match them to create styles all their own. 16, 2018 /PRNewswire/ - James Avery Artisan Jewelry, a Texas-based family owned jewelry retailer, announces the opening of its new Discovery Center and Store in San Antonio. ![]() Find beautiful charms, bracelets, rings, earrings & necklaces in a jewelry store near you. Whether we add a bit of twisted wire, a bit of turquoise, a dangling heart or a hammered texture, our designers set out to make each pair of hoops unique. James Avery Jewelry Counter in Dillards at Oak View Mall in Omaha. We also try to make each pair of hoops special. James Avery Jewelry is a family-owned company offering finely crafted jewelry designs. ![]() We carefully consider the materials asking ourselves if these hoops be silver, gold, bronze or a mix of metals? We pay attention to the size of each hoop to make sure we offer a selection of sizes that works well for different people with different tastes. James Avery Artisan Jewelry, Houston, Texas. This may seem like a simple thing to design, but so much goes into every pair of hoops we make. At James Avery Artisan Jewelry, we love earrings! Whether we're making classic hoops, heart earrings, cute studs for girls or stunning statement pieces for Mom, we approach the process with creativity and craftsmanship. ![]() Dremel drill stand1/22/2024 ![]() That was wrong it should have been 0.6mm. NB, I wrote I was drilling holes "as small as 0.4mm". Seems someone has review the 'official' dremel one vs the All - Thanks for the replies so far. I'd order that proxxon stand right now if I didn't have to buy a new tool to use it with. Wish they would make stands 'vender independant'. Any possibility of drilling 'other things', proxxon all the way. So I guess, if yo're doing PCB's only, the megaUK one might have the edge. Sure its less versatile - I'm tinking tahts for PCB's/flat pieces only - but the proxxon's vice and base is just gold. As for the stands, whilst the megaUK one looks basic, the dual pillars should stop any wandering travel. ![]() Given the two links, the proxxon rotary tool looks to me to be better than the dremel tool, it seems to be geared more for precision hobby work than dremels 'look how many attachments we have' approach. or losely holding the PCB down so a HSS can catch it and pull it centre - neither option is pleasant, professional or good for the bits. I've got quite good at aiming '2'o'clock' of the drill centre. For most apps that wouldn't be much of an issue,but for PCB holes < 0.8mm it snaps carbide bits quite often, and can mean off-centre holes when drill with a HSS. It has slight play during the travel which I cannot seem to get rid off no matter how much tweaking I do. **broken link removed** (jsut the stand). This was a poor decision on my part as I jsut went for the 'slightly' cheaper one avaliable: What DID annoy me was the relatively cheap drill stand I got for it. ![]() ![]() For the price I got it, £50 ex display, it was worth it, and hasn't failed me. It has no play on the collet/chuck, and the variable speed is only used for 'fast' for PCB carbide bits, and 'not so fast' for everything else. As far as the dremel tool itself goes, I haven't had trouble with mine (Dremel 300.). ![]() Mike clark chief architect zen ryzenian1/22/2024 ![]() ![]() But AMD is also discarding some of that efficiency advantage in the name of improving raw performance. We’ll take a look at more power data for the new Ryzen 7000 chips a bit later in our review, but the basic pattern is clear: Zen 4 can be a very power efficient architecture. In this case the 7950X has a 37% lead and 35% lead at 142W and 230W respectively. Meanwhile, increasing the socket power to 142 (5950X’s stock power) and then to 230W (7950X’s stock power) still produces a significant speed up in performance, but we’re certainly into the area of diminishing returns. For Ryzen 7000/Zen 4 on the other hand, AMD’s newer architecture fairs much better it still takes a hit from the TDP drop, but not by nearly as much. As a result, the 5950X needs to pull back on clockspeeds significantly at lower TDPs. This is something of a worst-case scenario for the older Ryzen chip, as it tended to be TDP limited even at is native TDP, and the relatively high idle power draw of the IOD and the rest of the platform further ate into that. In this case, pitting a 5950X against a 7950X with a maximum socket power of 88 Watts, AMD is seeing a 75% increase in performance on Cinebench R23 nT. The net result is that, according to AMD’s data, the company is seeing extensive power efficiency gains at lower TDPs. As we alluded to earlier when talking about AM5, one of AMD’s design goals was to provide more power to Ryzen 7000 chips so that they could go farther into the vf curve and keep their cores running at a higher frequency in MT-heavy workloads. How much of an improvement, in turn, depends on where on the voltage/frequency curve you end up. As a result, the Ryzen 7000 chips enjoy a significant power efficiency advantage versus the Ryzen 5000 chips. These include the 3 variable power rails, SVI3 VRM monitoring, and AMD’s lower-power Infinity Fabric Links. ![]() In other words, for the moment TSMC’s 5nm-class nodes are as good as it gets, putting AMD in a great position to take advantage of the benefits.Ĭoupled with this are all of the various platform power improvements that come with AM5 and the new 6nm IOD. Meanwhile TSMC’s competitors are either struggling by delivering less efficient 4nm-class nodes (Samsung), or they’ve yet to deliver a 4nm-class node at all (Intel). Thus far TSMC 5nm (and its 4nm derivative) is proving to be the powerhouse process of its generation, as TSMC’s clients have seen some solid gains in power efficiency and transistor density moving from 7nm to 5nm. We’ll start with a look at power efficiency, since power consumption plays a huge part in the Zen 4 story at both ends of the curve.īy tapping TSMC’s current-generation 5nm, process, AMD is enjoying the advantage of a full node shrink for their CPU cores. Zen 4 Power: More Efficient, More Power-Hungry There are some important changes here that are allowing AMD to deliver an average IPC increase of 13%, and combined with improvements to enable higher clockspeeds and greater power efficiency for both single-threaded and multi-threaded workloads, no part of AMD’s CPU performance has gone untouched. ![]() Instead, Zen 4 is a further refinement of AMD’s Zen 3 architecture, with AMD taking advantage of things like the new AM5 platform and TSMC’s 5nm process to further boost performance. For that, you’ll want to wait for Zen 5 in 2024. Still, it’s fair to say that AMD’s goal for the Zen 4 architecture has not been a radical overhaul of their core CPU architecture. And while this attention meant that AMD’s collective attention was split between the CPU cores and the rest of the platform, AMD’s CPU cores are far from being ignored here. Now that we’ve had a chance to take a look at the AM5 platform surrounding the new Ryzen 7000 chips, as well as the new IOD that completes the high-end Ryzen chips, let’s dive into the heart of matters: the Zen 4 CPU cores.Īs laid out in previous pages, a big element in AMD’s design goals for the Ryzen 7000 platform was to modernize it, adding support for things like PCIe 5.0 and DDR5, as well as integrating more fine-grained power controls. ![]() Zen 4 Architecture: Power Efficiency, Performance, & New Instructions ![]() Make pompom garland1/22/2024 ![]() ![]() Add a yellow pom pom after every six orange pom poms. Add two large wooden beads followed by another orange pom pom followed by two wooden beads and so on. Trim off excess yarn tail and string on assorted small wooden beads.Īdd your first orange pom pom to your garland by pushing your plastic needle through the exposed center of the pom. Push your needle under the top loop of your tassel and tie the two ends of the yarn together in a tight double knot close to the tassel. Thread your 6’ strand of worsted weight yarn onto your plastic needle. Repeat once more to create a second matching tassel! Secure wraps with a double knot and let the excess yarn hang down with the rest of your tassel. Pull on the yarn as you go to compress and create the tassel’s head. Wrap a new piece of yarn slightly below the top of your tassel 3-4 times. Open up your tassel and rotate the top strings 180 degree so that the knot is now on the underside of your tassel. Trim both strands of tied yarn to be even.Ĭut open all of the bottom loops of your tassel. Tighten knot and secure with a second knot. Tie a single knot (like the first step of tying your shoes) then gently remove yarn from Loome. Take a new piece of yarn and push it through the space in the center of your yarn.īring the yarn to the top surface of your Loome, opposite the side with the cut tails. ![]() Secure yarn in the same notch as the beginning tail and cut yarn close to the Loome. Secure tail of pink yarn in a notch on the wide side of the Loome tool. Repeat until you have 24 orange poms and three yellow poms! Cut a 2.5” inch circle from a piece of cardboard or cereal box, place it on top of your flattened pom pom and trim around the perimeter so that the flat pom pom is nice and round. ![]() Follow instructions here to learn how to properly tie and trim your pom pom.įluff out your pom pom pancake and flatten it so that the interior pom pom string is concealed. You can find all the steps for making perfect pom poms here in The Neon Tea Party’s free video lesson, How to Make Pom Poms!įor these poms, wrap yarn 140 total revolutions on the wide side of your Loome tool or a 2.25” piece of cardboard. *Supplies marked with a * are included in The Neon Tea Party’s Pom Pom & Tassel DIY Kit!įor this project, you’ll want to make 24 large orange pom poms and three large neon yellow pom poms.
Lego duplo mega bloks1/22/2024 ![]() ![]() Blocks are often assembled in sets or in figures by interlocking and connecting the pegs/studs in the plastic, rectangular blocks.Ģ. Lego and Mega Blocks are two brand names of construction-type toys as well as minifigures. In some stores, they can be difficult to find because they are mixed with other toy products.ġ. There are also some concerns about the Mega Blocks sets as difficult to assemble.Ĭompared to Lego, Mega Blocks are considered cheaper. However, Lego purists often discourage this because Mega Blocks have a dull color, loose connections, and low durability. Mega Blocks’ products are bigger in size and often used with Legos. Mega Blocks are produced by Mega Brands, a public company based in Canada. On the other hand, Mega Blocks is one of Lego’s competitors. All Lego products adhere to strict quality control and high durability standards. Lego blocks are known to have bright and brilliant colors and made of APS plastic. Lego aficionados also maintain many active online communities.Ĭompared with Mega Blocks, Legos are smaller and not right for small children. There are Lego movies, games, video games, competitions, and theme parks. ![]() Lego also cultivated its own subculture and following. Aside from being toys, Legos are now also considered collectibles. Lego was the first construction toy in history and one of the most recognized toy brands in the world. The Lego Group is the first company that produced plastic building toys. The company based its product Lego from the invention of Ole Kirk Christiansen. ![]() The company is a private company and is based in Denmark. Lego is built and produced by the Lego Group. Blocks can be assembled and connected in numerous ways and a variety of constructed objects can be made.Īside from construction blocks, both Lego and Mega Blocks also deal with other forms like minifigures, set themes, and models. The bottom of the block has the same number of holes to enable one block to link and interlock to one another. Each rectangular block has an 8-peg/stud design in even spaces. Both brand names of toys employ rectangular plastic blocks to create a theme set, standalone figures, and other applicable figures. Lego and Mega Blocks are two lines of construction-type toys. In the world of construction toys, both Lego and Mega Blocks are familiar names not just to children but to parents as well. ![]() Naval submarine drones1/22/2024 ![]() Want to write for Task & Purpose? Click here. We salute this F-15 fighter jet for rocking the most ‘Murica paint job ever.This Army video shows how much Ranger School has changed in 70 years.We salute the USS Daniel Inouye for flying its badass battle flag on the way into port.Video shows alleged Ukrainian drone swarm attack on Russian warships in Crimea.The Navy’s most advanced aircraft carrier is officially flying a brand new battle flag at sea.Waterborne uncrewed vehicles can even be turned into essentially guided torpedoes.ĭespite apparently not launched from a submarine, drone boats loaded with explosives were used in a two-pronged drone swarm attack on Russia’s Black Sea fleet in Sevastopol in October. The Navy has used other types of UUVs in search and rescue missions, such as when looking for a missing Argentine submarine in 2017. The 2022 edition of the Chief of Naval Operations Navigation Plan calls for having approximately 150 uncrewed vessels in its fleet in 2035.Īlthough much of the drone focus has been on aerial ones, maritime drones are useful both in reconnaissance and in offensive uses. The Navy meanwhile is also looking into the potential of uncrewed vessels. The military has been greatly expanding the use of drones in its operations, both in ways to integrate them into offensive capabilities and to defend against swarms from hostile forces. ![]() “When this … capability is deployed, every SSN will have the ability to serve as a UUV mothership,” Rear Adm. That would greatly expand the capabilities and operation range of the submarines, as well as allow the UUVs to be used multiple times more easily. It would also be capable of automated recovery. The new UUV would also be based on the REMUS 600, but would be able to be modified with different sensors and equipment depending on the mission. The Navy is currently using multiple UUVs, including the Razorback model drawn from the REMUS 600 design. The next step is to develop a new drone that can serve both offensive reconnaissance and EOD roles. Last year the Navy began testing the Razorbacks with submarines. The system would also let submarines safely scout and clear mines and other hazards in hostile seas. If that is widely implemented, it would allow submarines to serve as mobile bases for advanced recon missions. Get the latest military news, entertainment, and gear in your inbox daily. “While the submarine is moving, the UUV has to find that torpedo tube and drive in,” Perry said to reporters. The service has yet to implement them fleetwide, he said. Doug Perry, director of submarine warfare for the Office of Chief of Naval Operations. The Navy has tested and proved that it can recover medium-sized UUVs, per Rear. Houston was speaking at the Naval Submarine League’s annual symposium. Bill Houston called the launching part “easy,” but said the rest is tough, according to the U.S. Right now the 600-pound Razorback UUV that the Navy has requires a dry-dock storage system and needs to be recovered by divers by hand, a cumbersome and time consuming task. Submarine Force commander Vice Adm. The idea, Navy leaders say, is to turn the nuclear attack submarine fleet into UUV “motherships” that can launch uncrewed objects both for offensive and reconnaissance purposes and for explosive ordnance disposal. Navy is aiming to expand a system that will let submarines launch and recover uncrewed underwater vehicles (or UUVs). Navy photo by Mass Communication Specialist 3rd Class Jonah Stepanik/Released). 27, 2015) Mineman 3rd Class John Stephen-Torres, assigned to Commander, Task Group (CTG) 56.1, observes data from a MK 18 MOD 2 unmanned underwater vehicle (UUV) for a training evolution during a squadron exercise (SQUADEX). ![]() Hollywood wax museum los angeles ca1/22/2024 ![]() In 1979, Singh expanded his business operations after opening the Thousand Oaks Self Storage (now known as the Hollywood Storage Center). ![]() The fourth location opened in Myrtle Beach, South Carolina in 2014 at Broadway at the Beach. The next Hollywood Wax Museum was opened in Gatlinburg, Tennessee in 2007 and closed in 2010 to make way for the larger Hollywood Wax Museum Pigeon Forge attraction in Pigeon Forge, Tennessee that opened in May 2012. The group opened Hollywood Wax Museum Branson in Branson, Missouri in 1996, which was completely renovated in 2009 and was recognized with the 2011 Branson Beautification Award for improving an important stretch of the Highway 76 strip. 6767 Hollywood Blvd, Los Angeles, CA 90028-4623. There is also a Chamber of Horrors, featuring classic and current movie monsters. Wax figures and sets featuring replicas of celebrities continue to change regularly. The wax museum is fairly fun and there is a whole 'creepy' section devoted to horror movies. It is on Hollywood Blvd, near Highland Ave. ![]() The Hollywood Wax Museum building once housed the most exclusive hangout in Los Angeles: The Embassy Club. Restaurants near Hollywood Wax Museum, Los Angeles on Tripadvisor: Find traveler reviews and candid photos of dining near Hollywood Wax Museum in Los Angeles, California. ![]() In June 2012, the family was recognized as Heroes of Hollywood by the Hollywood Chamber of Commerce Community Foundation for their staunch and generous support of the Hollywood community. The former sawmill operator from Canada built the Museum's fame by befriending celebrities, gossip columnists, members of the foreign press association and fans.Īfter Singh's retirement, his sons and grandson have continued to own, operate and further the Hollywood Wax Museum's legacy. When Singh opened the Hollywood Wax Museum, the line to get in was 1/2 mile long. ![]() Solitaire games 2471/22/2024 ![]() ![]() One of the best things about 247 Blackjack is all the options it comes with! When you are on the home screen (or in the game, push the Menu button - three lines with three dots - in the bottom right to get to home screen - don't worry, you can resume!), click the middle Options button which looks like a wrench. Keep playing 247 Blackjack until your money is all gone - then restart! No need to wait additional time for more chips! If you are on a streak and need to leave your computer, no worries! Your fabulous money pile will be kept until you return! Just be sure to Resume your game when asked! As you win money watch your chips grow in denominations! Your highest money count will always be kept as your high record too, just so you always have something to strive for! It will not always win, but it is the best statistical chance you have, so give it a chance if you are stumped! ![]() This will tell you what move will be most statistically likely to win the hand you are holding in blackjack. If you want advice while you are playing, click the Advice button (speech bubble) in the bottom right corner. If you push, you keep your bet money but do not win anything additional. If you win, you get your bet money back PLUS that same amount from the dealer, YAY! If you win with Blackjack, you get your original bet back PLUS you win 1.5 times your bet from the dealer, WOOHOO! If you lose, the dealer takes your bet money. First you can win (as previously described), secondly you can lose (bust hand or have less than dealer hand), or you can push (have same hand - number count or Blackjack - as dealer). Once the Blackjack hand is played out, three outcomes can occur. If the dealer has an Ace showing, you can click the "Insurance" button (this means you will place a bet worth half your hand bet, which will be paid out if the dealer has Blackjack but will be taken if the dealer does not). You must then decide if you will "hit" (take another card from the deck), "stay" (keep the hand you are dealt), or "double" (you double your bet and are given only one more card). Once you click "deal" your bet is set, and two cards are dealt to the player face up and two cards are dealt to the dealer, one face up and one face down. Click the chip again to remove it back to your pile of money. ![]() In Blackjack, or 21, the player must decide what to bet before the hand. This can be accomplished by getting Blackjack (first two cards equal 21) without dealer Blackjack, having your final card count be higher than the dealers without exceeding 21, or by not exceeding 21 and dealer busting by exceeding their card count of 21. The object of Blackjack is the beat the dealer. ![]() Cards are counted as their respective numbers, face cards as ten, and ace as either eleven or one (in our game it will show on the counter as an 11 unless you are over 21). It is played with one or more decks of cards. Welcome to 24/7 Blackjack! Blackjack, also known to some as twenty-one, is one of the most popular casino games around - and also super simple to learn! This easy to use, simple Blackjack game will certainly become your new favorite on the web!īlackjack is a card game that pits player versus dealer. ![]() AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |